From Data to Dialogue: Turning NPI, CMS, and Open Payments Data into Sales Insights
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From Data to Dialogue: Turning NPI, CMS, and Open Payments Data into Sales Insights

Millions of open healthcare records hide valuable patterns. This post shows how pharma companies can connect public datasets (NPI registry, CMS prescriber

December 3, 2025NeoPharma Research Team

From Data to Dialogue: Turning NPI, CMS, and Open Payments Data into Sales Insights

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The United States Pharmaceutical Market is projected to reach $979.25 billion by 2033, from $638.86 billion in 2024, at a CAGR of 4.86% according to United States Pharmaceutical Market Forecast and Company. This growth presents a significant opportunity for pharmaceutical sales representatives and marketing managers to leverage public datasets, such as NPI, CMS, and Open Payments, to uncover high-potential doctors and tailor messaging effectively. By connecting these datasets, sales teams can turn data into meaningful sales conversations, driving revenue and market share. The pharmaceutical market size accounted for USD 1.5 Trillion in 2022 and is projected to achieve a market size of USD 2.8 Trillion by 2032, growing at a CAGR of 6.4% from 2023 to 2032 according to Pharmaceutical Market Size, Share | Forecast 2032.

The Current State

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The pharmaceutical market is experiencing significant growth, with the U.S. pharmaceutical market size estimated at USD 634.32 billion in 2024 according to U.S. Pharmaceutical Market Size | Industry Report, 2030. Pharmaceutical companies in the U.S. spent over USD 80 billion in 2023, indicating a substantial investment in sales and marketing efforts. Companies like Veeva, which supported 60% of the world’s pharmaceutical sales representatives by 2017 according to Peter Gassner: A Profile of Veeva's Vertical SaaS Strategy, are leveraging technology to enhance sales performance. Additionally, companies like Aktana are using AI decision-support platforms to synthesize data from a wide variety of sources, enabling more effective targeting and rep effectiveness according to Sourcing and Engaging Physicians for Pharma Sales in.... The U.S. pharmaceutical market size was valued at USD 679.25 billion in 2024 and is projected to surpass around USD 1,236.08 billion by 2034, registering a CAGR of 6.17% over the forecast period of 2025 to 2034 according to US Pharmaceutical Market Size and Growth 2025 to 2034.

The use of public datasets, such as NPI, CMS, and Open Payments, is becoming increasingly important for pharmaceutical sales teams. These datasets provide valuable insights into physician prescribing patterns, patient demographics, and market trends. For example, the Open Payments database, which tracks payments made by pharmaceutical companies to healthcare professionals, can help sales teams identify high-potential doctors and tailor their messaging effectively. Biohaven, for instance, paid hundreds of thousands of dollars in speaker honoraria to top prescribers according to Case 6:21-cv-06539-CJS Document 1 Filed 08/18/21 Page 1 of 132. By leveraging these datasets, sales teams can gain a competitive edge in the market and drive revenue growth. The global pharmaceutical grade salidroside market, valued at USD 423 million in 2024, is projected to grow, indicating a potential opportunity for pharmaceutical companies to expand their product offerings according to U.S. Pharmaceutical Market Size to Set to Reach USD... - BioSpace.

The Challenge

Despite the availability of public datasets, pharmaceutical sales teams face significant challenges in leveraging these datasets to drive sales performance. One of the primary challenges is the complexity of the data, which can be difficult to analyze and interpret. Additionally, the sheer volume of data available can be overwhelming, making it challenging for sales teams to identify the most relevant insights. Furthermore, the lack of standardization in data collection and reporting can make it difficult to compare data across different sources. For example, the NPI dataset may not be consistent with the CMS dataset, making it challenging to integrate the data and gain a comprehensive understanding of the market. The pharmaceutical market is expected to grow due to the increasing demand for pharmaceuticals in global public health according to Pharmaceutical Market Size, Share | Forecast 2032, which can lead to increased competition and complexity in the market.

Pharma sales teams have started leveraging artificial intelligence (AI) and machine learning tools to enhance targeting and rep effectiveness according to Sourcing and Engaging Physicians for Pharma Sales in.... However, the adoption of these technologies is not widespread, and many sales teams still rely on manual data analysis and traditional sales strategies. The lack of data standardization and integration can also lead to data silos, where different departments and teams have access to different data sources, making it challenging to gain a comprehensive understanding of the market. To overcome these challenges, sales teams need to invest in data analytics and integration technologies, as well as provide training and support to sales representatives to effectively leverage these datasets.

What's Working

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Despite the challenges, many pharmaceutical companies are successfully leveraging public datasets to drive sales performance. Companies like Aktana are using AI decision-support platforms to synthesize data from a wide variety of sources, enabling more effective targeting and rep effectiveness. Veeva, on the other hand, is providing sales teams with a comprehensive platform to manage customer relationships, track sales performance, and analyze market trends. By leveraging these technologies, sales teams can gain a competitive edge in the market and drive revenue growth. Additionally, companies like Biohaven are using the Open Payments database to identify high-potential doctors and tailor their messaging effectively.

The use of data analytics and integration technologies is also becoming increasingly important for pharmaceutical sales teams. By leveraging these technologies, sales teams can gain a comprehensive understanding of the market, identify trends and patterns, and develop targeted sales strategies. For example, sales teams can use data analytics to identify physicians who are most likely to prescribe a particular medication, and then tailor their messaging and sales approach to those physicians. The key to success is to invest in the right technologies and provide training and support to sales representatives to effectively leverage these datasets. By doing so, pharmaceutical companies can drive revenue growth, improve sales performance, and gain a competitive edge in the market.

The Road Ahead

The future of pharmaceutical sales is likely to be shaped by the increasing use of public datasets, AI, and machine learning technologies. As the pharmaceutical market continues to grow, sales teams will need to leverage these technologies to gain a competitive edge and drive revenue growth. The use of data analytics and integration technologies will become increasingly important, enabling sales teams to gain a comprehensive understanding of the market and develop targeted sales strategies. Additionally, the adoption of AI and machine learning technologies will continue to increase, enabling sales teams to automate routine tasks, identify trends and patterns, and develop predictive models to forecast sales performance.

The pharmaceutical market is expected to reach $979.25 billion by 2033, from $638.86 billion in 2024, at a CAGR of 4.86% according to United States Pharmaceutical Market Forecast and Company. To capitalize on this growth, pharmaceutical companies will need to invest in the right technologies and provide training and support to sales representatives to effectively leverage public datasets. By doing so, they can drive revenue growth, improve sales performance, and gain a competitive edge in the market. The U.S. pharmaceutical market size was valued at USD 679.25 billion in 2024 and is projected to surpass around USD 1,236.08 billion by 2034, registering a CAGR of 6.17% over the forecast period of 2025 to 2034 according to US Pharmaceutical Market Size and Growth 2025 to 2034.

Action Items

To leverage public datasets and drive sales performance, pharmaceutical sales representatives and marketing managers should consider the following key insights:

* Leverage public datasets, such as NPI, CMS, and Open Payments, to gain a comprehensive understanding of the market and identify high-potential doctors

* Invest in data analytics and integration technologies to synthesize data from a wide variety of sources and develop targeted sales strategies

* Provide training and support to sales representatives to effectively leverage these datasets and technologies

* Adopt AI and machine learning technologies to automate routine tasks, identify trends and patterns, and develop predictive models to forecast sales performance

Here are three specific next steps to take:

1. Conduct a thorough analysis of the public datasets available and identify the most relevant insights for your sales team

2. Invest in data analytics and integration technologies to synthesize data from a wide variety of sources and develop targeted sales strategies

3. Develop a comprehensive training program to support sales representatives in effectively leveraging these datasets and technologies to drive sales performance and revenue growth.

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